Inserting this into the numerator of eq. (3) and using eq. (1) to substitute the cofactors with the elements of the inverse matrix, we get:

$$ \begin{equation*} R =\frac{\sum_{j=1}^N d_{ij}(\mathbf{r}^{\mathrm{new}})\, C_{ij}(\mathbf{r}^{\mathrm{old}})} {\sum_{j=1}^N d_{ij}(\mathbf{r}^{\mathrm{old}})\, C_{ij}(\mathbf{r}^{\mathrm{old}})} = \frac{\sum_{j=1}^N d_{ij}(\mathbf{r}^{\mathrm{new}})\, d_{ji}^{-1}(\mathbf{r}^{\mathrm{old}})} {\sum_{j=1}^N d_{ij}(\mathbf{r}^{\mathrm{old}})\, d_{ji}^{-1}(\mathbf{r}^{\mathrm{old}})} \end{equation*} $$